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Liver homeostasis can also be determined by histopathological analysis and assigning a histopathological score including inflammatory infiltrate (portal, lobular, pericentral)

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Another limitation of GLP-1 RAs is that discontinuation commonly leads to substantial body weight regain, and many patients who regain weight subsequently restart GLP-1 RA therapy, resulting in a recurrent cycle of body weight loss and gain [10]

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