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B6 mice fed with a normal fat diet (Normal Diet) or HFD (DIO) received the following treatment regimens: saline (Saline), scExe4 donor DNA-loaded LNP (Donor), or scExe4 donor DNA plus Cas9-coding DNA-loaded LNP (Donor+Cas9)

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Data availability This study involves the analysis of de-identified Electronic Health Record (EHR) data via the nference Federated Clinical Analytics Platform

A healthy liver holds several years worth