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oIGF-1 at a concentration of 10 ng mL 1 in DMEM increased myoblast proliferation by 22% compared to DMEM alone ( p = 0.045 by post hoc analysis) (Figure 2)

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[PubMed] Gobburu JV, Agers H, Jusko WJ, Ynddal L

It is the same cascade native IGF-1 and insulin partially share, which is why IGF-1 LR3 is frequently used as a research tool for studying mTOR-dependent cellular processes under sustained receptor activation