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Neuraminidases 1 and 3 trigger atherosclerosis by desialylating low-density lipoproteins and increasing their uptake by macrophages

Anesthesia was administered prior to drug injections to ensure animal comfort and minimize stress

Importantly, this is a second opportunity for the reduction of NADP+ to NADPH

If interventions are not started, the increased demand for insulin can overload pancreatic -cells leading to pancreatic -cell failure, decreased insulin secretion, and uncontrolled glycemia (Figure 1)

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Compared to plasma and control arteries, stable plaques have increased CE containing polyunsaturated fatty acids (170), which have increased susceptibility to oxidation