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Nrf2, a key transcription factor that regulates oxidative stress and inflammation, plays a crucial role in inducing the bodys antioxidant and anti-inflammatory responses, such as regulating redox balance, energy metabolism, proteasomal degradation, drug metabolism and excretion, and mitochondrial physiological function

This helps reduce the risk of chasing one intervention while missing the underlying drivers of symptoms

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Combination treatment 24 weeks after monotherapy improved MRI-PDFF vs