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doi: 10.26355/eurrev_202011_23812 234 XieZShenPQuYXuJZhengCGaoYet al

Recent studies 12,13,14,15,16,17,18,19,20 have shown the clinical benefit of DDAVP in controlling the rate of serum sodium increase when combined with intravenous 3% sodium chloride (NaCl)

It is a chemical inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which catalyzes the methylation of nicotinamide using S-adenosylmethionine as the methyl donor