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normal functioning of the nervous system

The brain and gut interact through a complex network known as the gutbrainmicrobiota axis, and emerging studies suggest that the intestinal microbiota and their metabolites may play a significant role in the pathogenesis of Alzheimers disease

Due to the high metabolism of the brain and the characteristics of relatively low regeneration, the brain is sensitive to oxidative damage produced by ROS levels and enhanced oxidative states will also lead to excessive oxidation of lipids, proteins, DNA, and increased total iron content in the SNpc

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