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doi: 10.1073/pnas.0706778104

As the disease advances, ferroptosis-induced release of damage-associated molecular patterns (DAMPs), exosomal transmission, and immune evasion mechanisms further amplify neuroinflammation and cell damage, establishing a cascade of intercellular pathological propagation that accelerates neurodegeneration

Retrieved from Practice Committee of the ASRM

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Importantly, these cardiovascular benefits were demonstrated specifically in the LEADER population: patients with type 2 diabetes at high cardiovascular risk

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