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Antioxidants like N -acetylcysteine and glutathione effectively mitigate oxidative stress and inflammation, primarily through scavenging reactive oxygen species (224, 225)

These effects are mediated through restoration of gut microbial balance and repair of intestinal barrier integrity, thereby reducing the uremic toxin burden and alleviating cardiovascular and metabolic disorders [184]

Cortical spreading depression (CSD), characterized by a strong wave of neuronal depolarization accompanied by glial and vascular activation, is widely believed to underlie the aura phase of migraines (24)

The immediate activation of the adaptive ER stress response was reduced, but not blocked by GSTP1

doi: 10.1016/j.cca.2014.07.012

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