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Further structural modifications to BBR may improve its oral bioavailability and efficacy

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a Tethering mechanism: a TWO-SITE INTERACTION MODEL FOR THE Nrf2-Keap1 COMPLEXA TWO-SITE INTERACTION MODEL FOR THE Nrf2-Keap1 COMPLEX

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The three families of lipid oxidase (cyclooxygenases [COX], cytochromes P450 [CYPs], lipoxygenases [LOXs]) can convert free PUFA into lipid oxides, but it is the LOXs family that has the most significant impact on ferroptosis (XIE et al., 2022)