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Risk of Hypokalemia (Low Potassium) Treatment with methylcobalamin can result in a boost in blood cell production in people with severe B12 deficiency and may potentially trigger hypokalemia

Note: As of January 2023, Modifier JZ was introduced to attest that there was zero drug wastage, and at least one of these modifiers (JW or JZ) is now required on all applicable Medicare drug claims

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they can offer additional training or see if an alternative therapy exists

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This was a recommendation both in the James Lind Alliance Priority Setting Partnership which PAS initiated and funded and in the NICE Guideline on B12 Deficiency which PAS initiated