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Cloning and characterization of a putative Ca2+/H+ antiporter gene from Escherichia coli upon functional complementation of Na+/H+ antiporter-deficient strains by the overexpressed gene

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The mechanisms make scientific sense

Under hypoxic conditions, hypoxia-inducible factor-1 alpha (HIF-1) fails to undergo ubiquitination and degradation, then undergoes nuclear translocation to bind to promoters on the vascular endothelial growth factor gene, finally increasing the expression of HIF-1 and VEGF in endometriotic lesions

J Diabetes Investig 2019;10:699705 [DOI] [PMC free article] [PubMed] [Google Scholar] 53.Qiao Q, Ouwens MJ, Grandy S, Johnsson K, Kostev K