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As TriNetX is a global dataset we also utilized TriNetX Curated (TNX Curated) codes, which are similar terms combined to minimize redundancy of database coding, Anatomical Therapeutic Chemical (ATC), RxNorm, and ICD-9 coding systems

To understand which targets explain the senolytic activity of the SCLAs, we generated a small library of 76 small interfering (si)RNAs (4 siRNAs each against 19 targets)

11, 12, 13 On one hand, it was observed in preclinical animal studies that a significant number of animals developed medullary thyroid carcinomas after long-term treatment with GLP1 analogs

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