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Mientras que el componente GLP-1 reduce la ingesta calrica mediante la modulacin del vaciado gstrico y la sealizacin de saciedad central, y el componente GIP potencia la sensibilidad a la insulina y favorece el almacenamiento lipdico subcutneo seguro frente al visceral, el componente de glucagn acta como un interruptor catablico controlado

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Proglucagon processing in porcine and human pancreas