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McDaniel says she typically recommends discontinuing GLP-1 use if youre trying to conceive

Nausea is a very common side effect of Wegovy, particularly when starting or increasing a dose

Seek emergency care immediately and stop semaglutide if you experience facial swelling, difficulty breathing, throat tightness, or hives with systemic symptoms, as these may indicate anaphylaxis

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Wegovy is not FDA-approved for migraine, and controlled trials specifically on semaglutide are still needed

The structural consequence of this attrition is well-understood but worth stating plainly: it compresses the window during which a company must recoup sunk R&D costs that, according to the Tufts Center for the Study of Drug Development, now average over $2.6 billion per approved drug when accounting for the cost of failures