We dont know which of the many effects of these drugs is really helping with obesity
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Here is how each medication stands: Wegovy (semaglutide 2.4mg) FDA approved for chronic weight management in adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related health condition (June 2021) FDA approved for adolescents aged 12 and older with initial BMI at or above the 95th percentile (December 2022) FDA approved to reduce cardiovascular risk in adults with obesity or overweight and established cardiovascular disease (March 2024) Wegovy HD 7.2mg approved for adults on 2.4mg who need additional weight loss (March 2026) Zepbound (tirzepatide for weight loss) FDA approved for chronic weight management in adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related health condition (November 2023) FDA approved for moderate-to-severe obstructive sleep apnea in adults with obesity (December 2024, the first medication ever approved for this combination) Not currently approved for adolescents or for cardiovascular risk reduction as a primary indication Mounjaro (tirzepatide for type 2 diabetes) FDA approved as an adjunct to diet and exercise to improve blood sugar in adults with type 2 diabetes (May 2022) Not FDA approved for weight loss in people without type 2 diabetes, though it is sometimes prescribed off-label for that purpose Insurance coverage for weight loss purposes is typically limited without a type 2 diabetes diagnosis Saxenda (liraglutide 3mg) FDA approved for chronic weight management in adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related health condition (December 2014) FDA approved for adolescents aged 12 to 17 with initial body weight above 60kg and obesity (December 2020) One of the longest-running approvals in this class with a well-established safety record over many years of use Wegovy vs Zepbound vs Mounjaro vs Saxenda: who might each suit
Anyone telling a patient the shot itself will melt fat is overselling it
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If you are considering using compounded semaglutide, talk to your doctor about the risks and benefits
