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The GLP-1 medications - both semaglutide (which works on one receptor) and tirzepatide (with two receptors, glucose-dependent insulinotropic polypeptide (GIP) and GLP-1) - mimic a natural gut hormone that helps control blood sugar and promote weight loss by slowing digestion and increasing the feeling of fullness

Constipation : Try adding fiber slowly into your diet to help prevent constipation

Before use in laboratory research, the lyophilised powder must be reconstituted: dissolved back into solution with an appropriate sterile diluent

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Aging populations, sedentary lifestyles, and urbanization contribute to increasing rates of metabolic disorders, creating a larger target patient pool for GLP-1 therapies

The commentary accompanying the original paper highlighted these results as evidence that senescent cell elimination could produce systemic rejuvenation rather than isolated organ-specific improvements (Krimpenfort & Berns, 2017)