Given what we do understand about the potential action on cellular signaling pathways this could pose serious risk
On the other hand, the adverse events of GLP-1 drugs have been extensively characterized from large randomized trials with placebo controls and, in the United States, from reports derived from 12% of Americans who are currently taking these drugs
Standard Therapeutic Cycle (12 Weeks): Clinical trials frequently employed 12-week protocols, which provide sufficient duration for measurable metabolic changes while establishing safety through comprehensive monitoring
It is not available over-the-counter
Changhan David Lee and Pinchas Cohen at the USC Leonard Davis School of Gerontology published the first description of MOTS-c in 2015
These challenges stem from different views on sustainability, limited control over the private sector, and slow political decision-making