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The SHAPE real-world study found 83.5% of semaglutide users reached 2.4 mg versus only 25.9% of tirzepatide users at 15 mg, and outcomes still favored tirzepatide

For optimal results, combining medication with personalized lifestyle changes, such as a balanced diet and exercise, is key

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Although a recent clinical trial failed to show significant benefit, Scott Kanoski, PhD, professor of biological sciences at University of Southern California, cautions against closing the door on this area

Note: This chart is for informational purposes only

What lifestyle strategies can amplify the weight loss effects of semaglutide