While one person might experience significant nausea with semaglutide, they might tolerate tirzepatide better, or vice-versa, due to subtle differences in their pharmacological effects and how their body metabolizes them
Always discuss your needs with a licensed healthcare provider
When semaglutide patients switch to tirzepatide In the graph below, you can see that patients who switched from semaglutide to tirzepatide, either because of greater side effects on semaglutide or because they felt they hit a plateau on semaglutide, they continued to lose weight on tirzepatide
The SURMOUNT program also generated important data on metabolic health improvements beyond weight loss
10.1016/S0140-6736(21)02188-7 7 DubskyM.VelebaJ.SojakovaD.MarhefkovaN.FejfarovaV.JudeE
That said, many people notice appetite changes within the first one to two weeks