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Following bariatric surgery, particularly Roux-en-Y gastric bypass, rapid nutrient delivery to the distal small intestine triggers markedly elevated GLP-1 secretionoften several-fold higher than pre-operative levels

doi: 10.1002/cne.903550112

RosenstockJFriasJJastreboffADuYLouJGurbuzSet alRetatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: A randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA

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use within 7 days [1]