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Most clinics use 12 to 16 week trials with weight, body composition (DEXA where available), and side effect monitoring

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Consistent with that, HbA1c remained in the normal range (3.63.8%) for all groups and did not differ significantly ( Supplementary Table 9 ), reflecting that this DIO model, while obese and insulin-resistant, had not progressed to frank diabetes within the study duration

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It helps a bit with weight loss