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Herzig D, Suhner S, Roos J, et al

Slightly reduced GLP-1 concentrations after a meal in participants with impaired oral glucose tolerance and more severely impaired GLP-1 secretion in type 2 diabetic patients, as demonstrated in cross-sectional analyses, may translate into a progressive loss of the ability to secrete GLP-1 with advancing type 2 diabetes as part of the process of disease progression

Moreover, there are signals of increased incidence of cardiac arrhythmias associated with its use

Diabetes: doctors are told not to start new patients on GLP-1 agonists because of shortages

doi:10.1155/2017/4179326 [85] Murata S, Inoue K, Aomatsu T, Yoden A, Tamai H

Goldenberg R, Punthakee Z