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In inflammatory conditions, it helps normalize NO levels to prevent excessive oxidative stress

Disruptions in iron metabolism, lipid metabolism, and the collapse of cellular oxidative defense systems can accelerate the production of lipid peroxides, damaging the CNS and leading to secondary injuries in acute CNS injuries and NDDs (Ratan, 2020)

CD4 + T-helper cells stimulated in response to placental ischemia mediate hypertension during pregnancy

Another factor contributing to its popularity is its versatility

Sasaki-Hamada S, Sacai H, Oka JI

The honest caveat: animal studies especially rat studies do not always translate reliably to humans, and the research here has been dominated by a single group