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Oral bioavailability is estimated at approximately 38%
Dose efficiency
Temporarily reducing fibre and fat intake may help, focusing on plain foods like rice, toast, and bananas until symptoms improve
It also delays gastric emptying, inhibits glucagon release from pancreatic alpha cells, causes the proliferation of beta cells, and decreases their apoptosis
Another study found that there was an even higher risk of developing hypothyroidism in patients with type 1 diabetes who also had TPO antibodies they were 18 times more likely to develop hypothyroidism compared to patients with type 1 diabetes without TPO antibodies
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