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In some animal and clinical trials, GLP-1 analogs (Exendin-4, Liraglutide) have been shown to have neuroprotective effects on PD and AD ( .Given the correlation between PD and glucose metabolism disorders and energy conversion disorders, researchers have increasingly focused on the neuroprotective effects of GLP-1.GLP-1 receptor agonists provide neuroprotection through multiple pathways, including improving insulin sensitivity, reducing oxidative stress, and enhancing mitochondrial function, as shown in Figure 2

When cells become damaged and are replaced their DNA/RNA degrade into purine molecules which are then metabolized into uric acid