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Granulocyte/macrophage colony-stimulating factor influences angiogenesis by regulating the coordinated expression of VEGF and the Ang/Tie system

10.1016/j.jtemb.2020.126570 J Trace Elem Med Biol

Subbaratnam Muthukrishnan for reviewing an early version of the manuscript

For example, a co-crystallization strategy reveals that ML162 effectively targets all catalytic tetrad residues in GPX4 by interacting with Sec46, Gln81, Trp136, and Asn137, thereby completely obstructing the active site [218]

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