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As this study showed comparable exposures between the 1G and 2G formulations of oral semaglutide that met stringent regulatory bioequivalence criteria, it is considered unlikely that there will be any clinically meaningful differences in efficacy or safety between these formulations

2020 Feb 1 [cited 2025 Feb 28];21(4):1224

However, they are sometimes prescribed as part of long-term plans for weight management

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E., Charenton, C