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Vitamin B12 injection : For maximum bioavailability, especially in cases of severe deficiency or malabsorption, intramuscular injections of vitamin B12 offer direct absorption and are often prescribed to rapidly restore adequate levels

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From the brains, the hippocampi with entorhinal cortices were combined from both hemispheres and sliced at 0.5 mm in Hibernate AB (Transnetyx/BrainBits, #HAB 500, osmolarity adjusted to 298 mOsm with 5 M NaCl)

Such observational studies can be subject to unmeasured confounding, including confounding by indication, compared to RCTs [16]

Expecting to need a second session at 6 months for 2030% of cases is also realistic