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Proton magnetic resonance spectroscopy in obsessivecompulsive disorder: Evidence for reduced neuronal integrity in the anterior cingulate

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To uncover the underlying mechanisms, the researchers analyzed hippocampal tissue focusing on dentate gyrus, where they quantified neural progenitor proliferation and neurogenesis through BrdU, immunofluorescence for Sox2, GFAP, DCX and NeuN, and unbiased stereological cell counting

Henderson, N

Recently, it was shown that cysteine uptake via excitatory amino acid carrier 1 suppresses ischemia-induced neuronal death through promotion of hippocampal GSH synthesis in ischemic animal models (162)

PMC 1794290