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This means that a peptide with a 2-hour half-life administered three times daily will reach steady-state within approximately 10 hours, while a peptide with a 7-day half-life like Semaglutide requires roughly 35 days to reach steady state with weekly dosing

(2) Peptide therapy involves introducing exogenous (derived from external sources) peptides into the body to mimic the natural actions of our endogenous (produced within the body) peptides

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Keller, C

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