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In addition, available evidences also support VPA efficacy in a variety of epilepsy syndromes [159] including Lennox-Gastaut syndrome (dosage ranged from 500 mg/day to 1500 mg/day [160]), West syndrome (dosage at 30 mg/kg/day [161]) and Dravet syndrome (dosage ranged from 25 to a maximum of 60 mg/kg/day [162])