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Because there is some level of sympathetic tone on the heart, beta-blockers can reduce sympathetic influences that normally stimulate chronotropy (heart rate), inotropy (contractility), dromotropy (electrical conduction) and lusitropy (relaxation)

doi: 10.1038/s41419-022-04775-z 62 WuJLiuQZhangXTanMLiXLiuPet al