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To view a copy of this licence, visit About this article Cite this article Chaudhry, H., Rangra, N.K

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Characterized by an excessive accumulation of fat that impairs health, obesity increases the risk of developing serious comorbidities, such as cardiovascular disease, type 2 diabetes, musculoskeletal disorders, certain cancers, and psychological disorders (3, 4)

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They are all class B1 GPCRs, share significant sequence similarity (Usdin et al., 1993) and form secretin-VIP receptor family ( GIPR Expression The human GIP receptor (GIPR) gene is 13.8 kb long containing 14 exons

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Research Evidence Comparison# Mazdutide Research# Mazdutide has the largest Phase 3 evidence base of any GLP-1/glucagon dual agonist, with seven trials across the GLORY (obesity) and DREAMS (T2D) programs

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