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Due to the sufficient water content and reversible cross-linking properties of the dynamic hydrogel, which are highly analogous to the composition and function of natural NP tissue, it can become a viable therapeutic material in IDD

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Low levels of biotin may contribute to poor hair health, leading patients to notice increased hair breakage or shedding

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Further, MTX increased the expression of PERK (Figure 6B), GRP78 (Figure 6C), ATF4 (Figure 6D), and CHOP-10 (Figure 6E) in the liver compared to CTRL, indicating that ER stress is implicated in MTX-induced hepatotoxicity