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Despite earlier beliefs of AAVs being free of insertional mutagenesis, some studies suggest that AAV has a propensity to integrate randomly into the genome at double strand breaks (DSBs) [147], leading to tumorigenesis and liver cell hyperplasia in animals [148]

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Similarly, Vitamin D plays a crucial role in maintaining bone health

The safety and effectiveness of subcutaneous NOVOLOG were compared to regular human insulin in 596 type 1 diabetes adult, 187 pediatric type 1 diabetes, and 91 adult type 2 diabetes patients using NPH as basal insulin (see Tables 3, 4, 5)

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