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As monotherapy , a multicentre, randomised, double-blind, placebo-controlled and active-controlled Phase 2 dose-finding trial enrolled 706 adults with overweight or obesity (without diabetes) to once-weekly subcutaneous cagrilintide across doses of 0.3 to 4.5 mg over 26 weeks

Medical conditions associated with the metabolic syndrome such as type 2 diabetes, hypertension, obesity, and hyperlipidemia are all associated with NAFLD

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No significant treatment differences were observed for other thirst ratings or well-being ratings (data not shown)

It helps to release insulin and lowers the amount of glucose produced by the liver when glucose rises at mealtime