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People with kidney or liver disease should consult a provider before daily supplementation, and doses above 3000 mg/day should not be taken without medical guidance

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Equally, treatment with recombinant human IGF-1 (rhIGF-1) in children with severe IGF-1 deficiency, due to GHR-insensitivity, was shown to increase kidney length [132]

Who should never combine phentermine and tirzepatide Certain medical conditions create absolute contraindications for this combination

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10.1016/j.addr.2025.115572 45 MelmedS.PopovicV.BidlingmaierM.MercadoM.van der LelyA