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Gallbladder disease: Incretin-based therapies have been associated with an increased risk of cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation), as noted in the UK SmPCs for licensed comparators such as semaglutide and tirzepatide

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For many people, some degree of weight regain after stopping Wegovy is likely, as the appetite-suppressing effects reverse when treatment ends

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