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Thermo Fisher Scientific, Inc.) and incubated at room temperature for 20 min before being added to MDA-MB-436 cells, and the plate was incubated 48 h or 72 h under 5% CO2 at 37C

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The doubling time of each cell line was determined from the proliferation curves obtained

222201313007 and 22A201514042), the National Special Fund for State Key Laboratory of Bioreactor Engineering (No

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