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The main focus of this study is to investigate whether metformin and simvastatin synergistically target GLUTs and SREBP2, exploring the combined effects of these drugs on glioma metabolism, proliferation, and apoptosis

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A meta-analysis of 22 randomized controlled trials highlighted that patients with AD who received more than 12 weeks of melatonin treatment showed improvements in Mini-Mental State Examination scores, particularly in those with mild AD [219]