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doi: 10.1097/ADM.0b013e318193c993, 48 GearhardtA
Pasireotide (Figure 4A, cyclo(Hyp(Unk)-Phg-WKY(Bn)F)) can specifically binding to somatostatin receptor subtypes sst5 and sst1,2,3 and suppress the adrenocorticotropic hormone, IGF-1 and growth hormone secretion potently (Schmid, 2008)
Am J Phys Heart Circ Phys 304:H1085H1093 Wu FT, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS (2010) VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model