doi: 10.1080/10715762.2018.1468564 12 AlegreG
Chronic elevation of cortisol levels , as seen in Cushing's syndrome, is associated with multiple adverse effects including: Central obesity and metabolic syndrome Insulin resistance and type 2 diabetes Hypertension and cardiovascular disease Osteoporosis and increased fracture risk Mood disturbances, anxiety, and depression Impaired immune function and wound healing Psychological stress can affect cortisol patterns, though the relationship is complex and varies between individuals
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Dawson, 'From metabolism to mind: The expanding role of the GLP-1 receptor in neurotherapeutics', Neurotherapeutics , vol
Researchers also did not include female mice in the study, further limiting the data
If successful, this could allow for decreased doses of traditional drugs and fewer side effects