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Epitalon tiene eficacia clnica comprobada en humanos

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Nanchal R, Subramanian R, Karvellas CJ, Hollenberg SM, Peppard WJ, Singbartl K et al (2020) Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU: cardiovascular, endocrine, hematologic, pulmonary, and renal considerations

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DSIP had no sleep-inducing effect within the first hour post-injection, but other effects on sleep, such as a significant decrease in the percentage of stage I sleep, reduced awakenings, and increased total sleep time, were significant (t-test), although not significantly from the second to the sixth hour