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After pressure from activists, the agency formalized a compassionate use pathway in 1987

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However, its glucose-lowering effects require careful consideration in diabetic MS patients receiving insulin or sulfonylureas

The clinical efficacy is real, the safety profile is well-characterised, and the supply chain is now properly cold-chain-audited

According to the Summary of Product Characteristics (SmPC) approved by the Medicines and Healthcare products Regulatory Agency (MHRA), skin reactions including rash have been documented during clinical trials and post-marketing surveillance

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