Psychiatry 12 , 2335 (2007)
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It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2
Conversely, rapid appetite suppression can lead to undereating, which may affect energy levels or medication absorption for some antidepressants
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During the course, glucagon-like peptide-2 (GLP-2) enhanced intestinal epithelial cells proliferation and reduced gut permeability, thereby stabilizing the intestinal mucosal barrier
