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As other drug manufacturers join the GLP-1 race, Gan & Lee Pharmaceuticals in Beijing, China, is developing a novel biweekly GLP-1 for weight loss

Ren et al., 2024)

Typical dosage: 5 to 10 mg per day via subcutaneous injection for 10 to 20 consecutive days Administer in the evening, approximately 30 to 60 minutes before bed Cycle 1 to 2 times per year, with 4 to 6 months between courses Limitations: Virtually all Epithalon research originates from a single laboratory group in Russia

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In this study, a 23-h fasting regimen was implemented to simulate practical scenarios that might occur in humans

Microbiome analysis showed increased abundance of Firmicutes, Porphyromonadaceae, and Veillonellaceae and decreased Bacteroidetes, Ruminococcaceae, and Bacteroidaceae