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however, the kidneys may take up circulating citrulline and convert it to L-arginine

Moreover, the activities of Cu-Zn and Mn-dependent SOD, GPx, and catalase (CAT) were significantly downregulated in the abdominal adipose tissue of ovariectomized metabolic syndrome female rat model (to mimic the postmenopausal status) when compared to metabolic syndrome group without receiving treatment or the group received external estrogens [23]

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