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This systematic approach revealed hundreds of 20S proteasome substrates, including proteins undergoing specific N- or C-terminal cleavage, possibly for regulation

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Here, we have attempted to provide an overview of these similarities and differences, highlighting the metabolic characteristics of each type of antioxidant, including the transcriptional and enzymatic regulation of the three types of compounds

Recent data has linked xenobiotic exposure to an increased risk for a number of cardiometabolic diseases, including cardiovascular disease, obesity, and diabetes, and it may be that depletion of glutathione levels plays a significant role in this risk, or at the very least can serve as a risk biomarker

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