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In clinical trials, some patients reported bloating, indigestion, and stomach pain

The consistent finding is that creatine, when combined with resistance training, helps preserve significantly more lean mass compared to resistance training alone during caloric restriction

This is the chart you will reference week after week as you titrate upward

The jump from 0.5 mg to 1.0 mg is the largest proportional increase in the entire titration schedule, doubling your dose again

Weeks 58: Visible Progress Begins As doses gradually increase, many patients begin noticing measurable changes on the scale

Patients on the 7.2 mg weekly dose achieved an average weight loss of 20.7% of starting body weight over 72 weeks, compared to 17.5% at the standard 2.4 mg dose